Automated Patch Clamp
IonFlux Mercury 16
Patch Clamp Automation at the Price of Manual
Your new lab partner
16 independent recordings
8 parallel & independent experiments.
SBS Standard 96 well Plates. 144 data points per plate
Flexible synchronous assays
Continuous flow of solutions and compounds with integrated wash steps for maximum assay stability
In-plate fast solution exchange without the need for compound pipette stacking
Single cell giga-ohm seal recordings and
ensemble recordings (20 cells) with no artificial averaging
Integrated temperature control (ambient to
40 degrees). Available cooling system.
Independent cell source for multiple cell types screening at the same time (up to 8)
Touch screen operation and integrated software for assay development and analysis
Compatibility with XLFit templates for automatic IC/EC50 reporting
Optional current clamp
Upgradable to InFlux Mercury HT
700 Data points per hour
Investigating Potent Blockers of TRPM8
IonFlux 16 was used in a recent study aiming to discover novel TRPM8 channel block using automated patch clamp combined with ligand-based virtual screening.
Predicting Unwanted Drug/Heart Interactions with Artificial Intelligence
IonFlux 16 technology was featured in a recent Nature Scientific Reports article describing a study about predicting hERG-induced cardiotoxicity using advanced computational modeling of drug/receptor interaction.