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At Fluxion, we’re passionate about delivering cell-based and cell-free solutions that facilitate the transformation of research discoveries into new ways to diagnose and treat patients. By characterizing molecular and cellular mechanisms of disease, Fluxion’s platforms help bridge the translational medicine gap, enabling rapid advances in disease research, drug discovery, and the development of diagnostic tests.

Automated Patch Clamp

IonFlux Mercury HT

Most affordable high throughput automated patch clamp on the market

Flexible Ion Channel Assays in 384 well plates

The IonFlux Mercury HT takes all the technology of the IonFlux Mercury 16 and multiplies the throughput by 4. With 64 amplifiers, continuous flow and extremely flexible liquid exchange, the IonFlux Mercury HT can sometimes be the only means to achieve higher throughput with extremely complicated flow-dependent ion channel assays. Using 384 well plates with integrated microfluidics, IonFlux HT can deliver a complete experiment with a few µl of compound usage. With the included liquid handling robot for plate preparation and compound dilution, IonFlux Mercury HT is the complete solution for lead to data for ligand gated and voltage gated ion channel assays. 
 
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Mercury Front Shadow-1

 

Features

64 independent recordings

32 parallel & independent experiments.

SBS Standard 384 well Plates. >500 data points per plate

Flexible synchronous assays

Continuous flow of solutions and compounds with integrated wash steps for maximum assay stability

In-plate fast solution exchange without the need for compound pipette stacking

Single cell giga-ohm seal recordings and
ensemble recordings (20 cells) with no artificial averaging

Integrated temperature control (ambient to
40 degrees). Available cooling system.

Independent cell source for multiple cell types screening at the same time (up to 32)

Touch screen operation and integrated software for assay development and analysis

Compatibility with XLFit templates for automatic IC/EC50 reporting

Optional current clamp

Included automated liquid handling robot for plate preparation and compound dilution (Mercury Automate)

 

2500 Data points per hour

Customer Spotlight

Potentiation of GABA receptors and idiopatic hypersomnia

IonFlux Mercury HT was recently used in a recent study correlating the existence of naturally occurring positive allosteric modulators of GABAA receptors in extracted cerebrospinal fluid of idiopathic hypersomnia patients. 

Andy

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