Automated Patch Clamp
IonFlux Mercury HT
Most affordable high throughput automated patch clamp on the market
Flexible Ion Channel Assays in 384 well plates
64 independent recordings
32 parallel & independent experiments.
SBS Standard 384 well Plates. >500 data points per plate
Flexible synchronous assays
Continuous flow of solutions and compounds with integrated wash steps for maximum assay stability
In-plate fast solution exchange without the need for compound pipette stacking
Single cell giga-ohm seal recordings and
ensemble recordings (20 cells) with no artificial averaging
Integrated temperature control (ambient to
40 degrees). Available cooling system.
Independent cell source for multiple cell types screening at the same time (up to 32)
Touch screen operation and integrated software for assay development and analysis
Compatibility with XLFit templates for automatic IC/EC50 reporting
Optional current clamp
Included automated liquid handling robot for plate preparation and compound dilution (Mercury Automate)
2500 Data points per hour
Potentiation of GABA receptors and idiopatic hypersomnia
IonFlux Mercury HT was recently used in a recent study correlating the existence of naturally occurring positive allosteric modulators of GABAA receptors in extracted cerebrospinal fluid of idiopathic hypersomnia patients.