Enhanced solution flow control improves accuracy and precision of ligand-induced current responses of Acetylcholine and GABA receptors.


Ali Yehia, PhD
Fluxion Biosciences

Comprehensive studies of ligand-gated receptors depend on reliable, accurate and repetitive responses of said receptors to the co-application of agonists. If a liquid exchange is not precise and complete, receptor desensitization will ultimately act as the limiting factor in an assay.

What will be discussed:
Data will be presented showing how the new flow control technology implemented in IonFlux Mercury can enhance existing ligand-gated assays (Nicotinic and GABA receptors) limiting receptor desensitization and increasing reproducibility of currents.


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