High Throughput Ion Channels Assays with No Compromise


IonFlux provides the highest degree of control over fluidics for specialized ion channel assays. With its unique microfluidic plates, IonFlux is the only system where all cell recordings and liquid exchange are performed within the plate proper. Without the hindrance of liquid handlers, the system advances high throughput ion channel experiments by providing unique attributes that permit specialized assays, impossible or impractical using other asynchronous systems:

  1. Parallel and rapid exchange of solution

  2. Continuous flow of extracellular solutions and compound throughout the whole experiment.

  3. High Quality recordings from 16 or 64 amplifier channels

  4. Available temperature control with positive feedback

The specialized characteristics related to its unique liquid exchange permits IonFlux to perform ligand binding, allosteric modulation, multiple agonists, and voltage- and temperature-sensitive assays with flexibility and ease. Complex ligand-gated assays, requiring serial exchange of solutions, can now be screened at the same speed and ease as voltage-gated assays.


IonFlux Mercury 16

IonFlux Mercury represents the next generation in the IonFlux automated patch clamp system. The new system adds features such as remote and touch screen experiment execution, highly extended recording times, new streamlined fluid exchange system, standardized temperature control, and optional current clamp. IonFlux Mercury is the most compact yet full featured stand-alone high throughput automated patch clamp instrument on the market.

IonFlux Mercury HT

The most advanced high throughput automated patch clamp system for flow dependent assays

The IonFlux Mercury HT takes all the technology of the IonFlux Mercury 16 and multiplies the throughput by 4. With 64 amplifiers, continuous flow and extremely flexible liquid exchange, the IonFlux Mercury HT can sometimes be the only means to achieve higher throughput with extremely complicated flow-dependent ion channel assays.


For more information about IonFlux line of products